The Mercedes-Benz S-Class S 450 4MATIC in Europe produced from 2026 to today offers a mild hybrid petrol powertrain with 381 hp, an automatic transmission and all-wheel drive. Below you find all technical data regarding the powertrain, performance, weights, consumption and more.
| Total powertrain | |
| Fuel type | Mild hybrid petrol |
| System power | 280 kW (381 hp) |
| System power range | 5000–6100 rpm |
| System torque | 560 Nm |
| System torque range | 2000–4500 rpm |
| Transmission type / Gears | Automatic |
| Drivetrain | All-wheel drive |
| Combustion engine | |
| Engine type / Number of cylinders | In-line / 6 |
| Valves per cylinder | 4 |
| Displacement | 2999 cc |
| Bore | 83.00 mm |
| Stroke | 92.35 mm |
| Compression ratio | 10.5 :1 |
| Electric motors | |
| Power of electric motor 1 | 17 kW (23 hp) |
| Torque of electric motor 1 | 205 Nm |
| Acceleration 0–100 km/h | 4.9 s |
| Top speed | 250 km/h |
| Front tyre size (standard) | 235/55 R18 |
| Rear tyre size (standard) | 235/55 R18 |
| Front wheel size (standard) | 8J x 18" |
| Rear wheel size (standard) | 8J x 18" |
| Front brake type | Ventilated discs |
| Rear brake type | Ventilated discs |
| Front brake diameter | 370 mm |
| Rear brake diameter | 320 mm |
| Kerb weight | 2165 kg |
| Payload | 660 kg |
| Gross vehicle weight | 2825 kg |
| Towing capacity (unbraked) | 750 kg |
| Towing capacity (braked) | 2100 kg |
| Fuel consumption | |
| WLTP consumption combined | 8.1–8.9 L/100 km |
| Fuel tank capacity | 76 L |
| CO₂-emissions | |
| WLTP CO₂ combined | 185–203 g/km |
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